Research progress update on Seneca Valley Virus published online at Swine Health Information Center

Seneca Valley Virus research updates online cover shedding patterns, genetic diversity, outbreak investigations, disinfectant evaluations, prevalence studies, as well as development of diagnostic testing. All research projects funded by Swine Health Information Center send regular updates to pork industry stakeholders. These are published on the SHIC website at

The most recent SVV research update reports on-target progress regarding development of reagents and serological assays for Seneca Valley Virus. Rabbit polyclonal antisera produced against whole SVV and individual expressed proteins has been evaluated and is ready to be shared with other researchers and diagnostic laboratories. Good progress has been made on several diagnostic serology prototype tests and selected tests are now being evaluated for sensitivity and specificity. Project deliverables on this specific project will include specific antibody reagents for IHC and fluorescence staining for diagnostic and pathogenesis studies. Also included will be a range of prototype serological assays for improved diagnostic surveillance and prevalence surveys.

SVV clinical cases continue to arise. SVV lesions are clinically indistinguishable from FMD. Each discovery of blisters on the nose or hyperemia of the coronary band, hoof pad or interdigital lesions should first be investigated to ensure FMD is ruled out. Often the first clinical sign observed is lameness. SVV lesions must be reported immediately to SAHO or federal veterinary officials.