SHIC Collaborates on Minimum Infectious Dose of FMD in Feed and Mitigation Strategies

The Swine Health Information Center (SHIC) will collaborate directly with USDA Ag Research Service on Plum Island, USDA-APHIS, National Pork Board, and other key researchers to determine the minimum infectious dose (MID) of foot and mouth disease (FMD) virus needed to infect pigs via feed ingredients using normal feeding behaviors. Simultaneously, this project will look at the effectiveness of possible mitigants being added to the feed to help neutralize the virus. To date, no study has looked at the dose needed to infect a pig via feed, using normal feeding behaviors. And the collaborations will enable the direct use of FMD instead of having to use a surrogate. Successful completion of the project will provide critical knowledge pertaining to the risk of introduction of FMD into the US pig production system by imported feed components as well as potential mitigation of that risk.

Researchers state the overall goals of this jointly SHIC-funded project are to investigate the MID of FMD in pigs exposed to two variants of the virus through natural feeding behavior and to assess the efficacy of select feed additives (mitigants) in reducing the risk of transmission of FMD following ingestion of contaminated and treated feed. These survival and mitigation trials will be designed and performed in alignment with previous and ongoing SHIC-funded studies led by Drs. Scott Dee, Diego Diel, and Megan Niederwerder who are performing similar studies on other important transboundary disease pathogens of pigs.

Part of that research showed the potential for FMD to be transported via feed ingredients from China to the US through surviving the 37-day trip duration. This work used Seneca Valley A virus as a surrogate for FMD and suggests the ability for FMD to survive in multiple feed components including soybean meal, DDGS, lysine, choline, and vitamin D for the time necessary for transpacific passage to pig rearing regions. And past studies have shown pigs are highly susceptible to oral transfer of FMD when dosed under laboratory conditions.

Funded by America’s pork producers to protect and enhance the health of the US swine herd, the Swine Health Information Center focuses its efforts on prevention, preparedness, and response. As a conduit of information and research, SHIC encourages sharing of its publications and research for the benefit of swine health. Forward, reprint, and quote SHIC material freely. For more information, visit http://www.swinehealth.org or contact Dr. Paul Sundberg at psundberg@swinehealth.org.

June 26, 2018

SHIC Collaborates on Minimum Infectious Dose of FMD in Feed and Mitigation Strategies

The Swine Health Information Center (SHIC) will collaborate directly with USDA Ag Research Service on Plum Island, USDA-APHIS, National Pork Board, and other key researchers to […]
June 20, 2018

SHIC Drives Improved Readiness for Emerging Disease in US Pork Industry with PCR Catalog

When porcine epidemic diarrhea virus (PEDv) hit the US in 2013, we could not effectively test for it. The North American pork industry learned a lesson […]
June 19, 2018

SHIC Board Approves Project to Examine Future Industry Needs and Confirms Mission Statement

Always concerned about the future of the pork industry, the Swine Health Information Center (SHIC) Board of Directors June meeting included review of the organization’s mission […]
June 12, 2018

SHIC Swine Disease Reports Help to Stay Updated on Global and Domestic Disease Trends

The Swine Health Information Center (SHIC) developed two systems for near real-time domestic and global swine disease monitoring. The information made available by these systems will […]
June 11, 2018

June 2018 SHIC eNewsletter

SHIC Swine Disease Reports Help to Stay Updated on Global and Domestic Disease Trends
SHIC Funded Research Results in PKV Detection Tool
SHIC Sponsored Research Develops System to Help Farms Strategically Target Disease Monitoring and Control
Need More Diagnostics? SHIC Can Help!